# Publications Download 115 citations download- [BibTeX](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=bibtex) - [EndNote X3 XML](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=endnote8) - [EndNote 7 XML](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=endnote7) - [Endnote tagged](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=tagged) - [Marc](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=marc) - [PubMedId](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=pubmed_id) - [RIS](/bibcite/export?pager_style=standard_pager&number_of_items=15&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_publicationcategory1%5D&&&format=ris) ### Forthcoming Tyssowski KM, Cohen JD, Guo JZ, Richardson PR, Cortina KE, Smith IH, Eijogu DC, Hantman AW, Hoekstra HE. [Evolutionary expansion of the corticospinal system is linked to dexterity in Peromyscus mice ](/publication/evolutionary-expansion-corticospinal-system-linked-dexterity-peromyscus-mice-0). bioRxiv. 2025; Tyssowski KM, Cohen JD, Guo JZ, Richardson PR, Cortina KE, Smith IH, Eijogu DC, Hantman AW, Hoekstra HE. [Evolutionary expansion of the corticospinal system is linked to dexterity in Peromyscus mice ](/publication/evolutionary-expansion-corticospinal-system-linked-dexterity-peromyscus-mice-0). bioRxiv. 2025; - add\_circle\_outline do\_not\_disturb\_on Abstract Animals have evolved behavioral variation to adapt to distinct environmental features. The expansion of neuron number is a potential neural mechanism underlying this behavioral adaptation. Corticospinal neurons (CSNs) are a classic example: an expansion... ### 2026 Mier IF, Arlt MF, Lawson AM, Dulka EA, Wooldridge TB, Hoekstra HE, Mueller JL. [An X-to-autosome-to-Y chromosome amplified retrogene family functions in spermatids ](/publication/x-autosome-y-chromosome-amplified-retrogene-family-functions-spermatids). Current Biology. 2026; Mier IF, Arlt MF, Lawson AM, Dulka EA, Wooldridge TB, Hoekstra HE, Mueller JL. [An X-to-autosome-to-Y chromosome amplified retrogene family functions in spermatids ](/publication/x-autosome-y-chromosome-amplified-retrogene-family-functions-spermatids). Current Biology. 2026; - add\_circle\_outline do\_not\_disturb\_on Abstract Mammalian Y chromosomes acquire lineage-specific gene families1,2,3,4,5 with spermatogenic functions in male fertility,1,2,6,7,8 a mechanism that counters Y chromosome decay. However, in most mammals, the mechanisms by which Y chromosomes acquire new gene... ### 2025 Howell EK, Baier F, Hoekstra HE, Payseur BA. [The Genomic Imprint of Chromosomal Inversions and Demographic History in Island Populations of Deer Mice ](/publication/genomic-imprint-chromosomal-inversions-and-demographic-history-island-populations-deer). Molecular Biology and Evolution . 2025; Howell EK, Baier F, Hoekstra HE, Payseur BA. [The Genomic Imprint of Chromosomal Inversions and Demographic History in Island Populations of Deer Mice ](/publication/genomic-imprint-chromosomal-inversions-and-demographic-history-island-populations-deer). Molecular Biology and Evolution . 2025; - add\_circle\_outline do\_not\_disturb\_on Abstract Populations that colonize islands experience novel selective pressures, fluctuations in size, and changes to their connectivity. Owing to their unique geographic setting, islands can function as natural laboratories in which to examine the interactions... Baier, Reinhard K, Tong V, Murmann J, Farrow K, Hoekstra HE. [The neural basis of defensive behaviour evolution in Peromyscus mice](/publications/neural-basis-defensive-behaviour-evolution-peromyscus-mice). Nature. 2025; Baier, Reinhard K, Tong V, Murmann J, Farrow K, Hoekstra HE. [The neural basis of defensive behaviour evolution in Peromyscus mice](/publications/neural-basis-defensive-behaviour-evolution-peromyscus-mice). Nature. 2025; - add\_circle\_outline do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/2023.07.04.547734v1.full_.pdf) Evading imminent threat from predators is critical for animal survival. Effective defensive strategies can vary, even between closely related species. However, the neural basis of such species-specific behaviours remains poorly understood1-4. Here we find... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/2023.07.04.547734v1.full_.pdf) Gozashti L, Harringmeyer O, Hoekstra. H. [How repeats rearrange chromosomes: The molecular basis of chromosomal inversions in deer mice.](/publication/how-repeats-rearrange-chromosomes-molecular-basis-chromosomal-inversions-deer-mice) Cell Reports. 2025;44(5). Gozashti L, Harringmeyer O, Hoekstra. H. [How repeats rearrange chromosomes: The molecular basis of chromosomal inversions in deer mice.](/publication/how-repeats-rearrange-chromosomes-molecular-basis-chromosomal-inversions-deer-mice) Cell Reports. 2025;44(5). - add\_circle\_outline do\_not\_disturb\_on Abstract Large genomic rearrangements, such as chromosomal inversions, can play a key role in evolution, but the mechanisms by which these rearrangements arise remain poorly understood. To study the origins of inversions, we generated chromosome-level *de novo* geno... Chen J, Richardson PR, Kirby C, Eddy SR, Hoekstra HE. [Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice](/publication/cellular-evolution-hypothalamic-preoptic-area-behaviorally-divergent-deer-mice). eLife. 2025; Chen J, Richardson PR, Kirby C, Eddy SR, Hoekstra HE. [Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice](/publication/cellular-evolution-hypothalamic-preoptic-area-behaviorally-divergent-deer-mice). eLife. 2025; - add\_circle\_outline do\_not\_disturb\_on Abstract Genetic variation is known to contribute to the variation of animal social behavior, but the molecular mechanisms that lead to behavioral differences are still not fully understood. Here, we investigate the cellular evolution of the hypothalamic preoptic... ### 2024 Kingsley EP, Hager E, Lassance JM, Tuner K, Harringmeyer O, Kirby C, Neugebroen B, Hoekstra HE. [Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development](https://www.nature.com/articles/s41559-024-02346-3). Nature Ecology and Evolution. 2024;8. Kingsley EP, Hager E, Lassance JM, Tuner K, Harringmeyer O, Kirby C, Neugebroen B, Hoekstra HE. [Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development](https://www.nature.com/articles/s41559-024-02346-3). Nature Ecology and Evolution. 2024;8. - add\_circle\_outline do\_not\_disturb\_on Abstract Variation in the size and number of axial segments underlies much of the diversity in animal body plans. Here, we investigate the evolutionary, genetic, and developmental mechanisms driving tail-length differences between forest and prairie ecotypes of deer... Kautt A, Chen J, Lewarch CL, Hu C, Turner K, Lassance JM, Baier F, Bedford NL, Bendesky A, Hoekstra HE. [Evolution of gene expression across brain regions in behaviourally divergent deer mice](/publications/evolution-gene-expression-across-brain-regions-behaviourally-divergent-deer). Molecular Ecology. 2024;(e17270). Kautt A, Chen J, Lewarch CL, Hu C, Turner K, Lassance JM, Baier F, Bedford NL, Bendesky A, Hoekstra HE. [Evolution of gene expression across brain regions in behaviourally divergent deer mice](/publications/evolution-gene-expression-across-brain-regions-behaviourally-divergent-deer). Molecular Ecology. 2024;(e17270). - add\_circle\_outline do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/molecular_ecology_-_2024_-_kautt_-_evolution_of_gene_expression_across_brain_regions_in_behaviourally_divergent_deer_mice.pdf) The evolution of innate behaviours is ultimately due to genetic variation likely acting in the nervous system. Gene regulation may be particularly important because it can evolve in a modular brain-region specific fashion through the concerted action of *c*... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/molecular_ecology_-_2024_-_kautt_-_evolution_of_gene_expression_across_brain_regions_in_behaviourally_divergent_deer_mice.pdf) ### 2023 Gozashti L, Feschotte C, Hoekstra H. [Transposable element competition shapes the deer mouse genome.](/publications/transposable-element-competition-shapes-deer-mouse-genome) Molecular Biology and Evolution. 2023;40(4):msad069. Gozashti L, Feschotte C, Hoekstra H. [Transposable element competition shapes the deer mouse genome.](/publications/transposable-element-competition-shapes-deer-mouse-genome) Molecular Biology and Evolution. 2023;40(4):msad069. - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/gozashtil_2022.10.18.512801v3.full_.pdf) - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/gozashtil_2022.10.18.512801v3.full_.pdf) Jourjine N, Woolfolk M, Sanguinetti-Scheck J, Sabatini J, McFadden S, Lindholm A, Hoekstra H. [Two pup vocalization types are genetically and functionally separable in deer mice.](/publications/two-pup-vocalization-types-are-genetically-and-functionally-separable-deer) Current Biology. 2023;33(7):1237–1248.e4. Jourjine N, Woolfolk M, Sanguinetti-Scheck J, Sabatini J, McFadden S, Lindholm A, Hoekstra H. [Two pup vocalization types are genetically and functionally separable in deer mice.](/publications/two-pup-vocalization-types-are-genetically-and-functionally-separable-deer) Current Biology. 2023;33(7):1237–1248.e4. - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/jourjine_n2022.11.11.516230v1.full_.pdf) - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/jourjine_n2022.11.11.516230v1.full_.pdf) Harringmeyer O, Hu C, Metz H, Mihelic E, Rosher C, Sanguinetti-Scheck J, Hoekstra H. [A single genetic locus lengthens deer mouse burrows via motor pattern evolution](https://www.biorxiv.org/content/10.1101/2023.07.03.547545v2.abstract). bioRxiv 2023.07.03.547545. 2023; Harringmeyer O, Hu C, Metz H, Mihelic E, Rosher C, Sanguinetti-Scheck J, Hoekstra H. [A single genetic locus lengthens deer mouse burrows via motor pattern evolution](https://www.biorxiv.org/content/10.1101/2023.07.03.547545v2.abstract). bioRxiv 2023.07.03.547545. 2023; ### 2022 Hager E, Harringmeyer OS, Wooldridge TB, Theingi S, Gable JT, McFadden S, Neugeboren B, Turner KM, Hoekstra HE. [A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes](https://www.biorxiv.org/content/10.1101/2021.01.21.427490v1). Science. 2022;377 (6604):399–405. Hager E, Harringmeyer OS, Wooldridge TB, Theingi S, Gable JT, McFadden S, Neugeboren B, Turner KM, Hoekstra HE. [A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes](https://www.biorxiv.org/content/10.1101/2021.01.21.427490v1). Science. 2022;377 (6604):399–405. - add\_circle\_outline do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/hager_2022_science.pdf) How locally adapted ecotypes are established and maintained within a species is a long-standing question in evolutionary biology. Using forest and prairie ecotypes of deer mice (*Peromyscus maniculatus*), we characterized the genetic basis of variation in... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/hager_2022_science.pdf) Harringmeyer OS, Hoekstra HE. [Massive inversion polymorphisms shape the genomic landscape of deer mice](/publications/massive-inversion-polymorphisms-shape-genomic-landscape-deer-mice). Nature Ecology & Evolution. 2022;6:1965–1979. Harringmeyer OS, Hoekstra HE. [Massive inversion polymorphisms shape the genomic landscape of deer mice](/publications/massive-inversion-polymorphisms-shape-genomic-landscape-deer-mice). Nature Ecology & Evolution. 2022;6:1965–1979. - add\_circle\_outline do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/harringmeyer_2022.pdf) Chromosomal inversions are an important form of structural variation that can affect recombination, chromosome structure and fitness. However, because inversions can be challenging to detect, the prevalence and hence the significance of inversions... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/harringmeyer_2022.pdf) Bedford NL, Weber JN, Tong W, Baier F, Kam A, Greenberg RA, Hoekstra HE. [Interspecific variation in cooperative burrowing behavior by Peromyscus mice](/publications/interspecific-variation-cooperative-burrowing-behavior-peromyscus-mice). Evolution Letters. 2022;https://doi.org/10.1002/evl3.293. Bedford NL, Weber JN, Tong W, Baier F, Kam A, Greenberg RA, Hoekstra HE. [Interspecific variation in cooperative burrowing behavior by Peromyscus mice](/publications/interspecific-variation-cooperative-burrowing-behavior-peromyscus-mice). Evolution Letters. 2022;https://doi.org/10.1002/evl3.293. - add\_circle\_outline do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/bedford_2022_evollett.pdf) Animals often adjust their behavior according to social context, but the capacity for such behavioral flexibility can vary among species. Here, we test for interspecific variation in behavioral flexibility by comparing burrowing behavior across three... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/bedford_2022_evollett.pdf) Khadraoui M, Merritt J, Hoekstra H, Bendesky A. [Post-mating parental behavior trajectories differ across four species of deer mice.](/publications/post-mating-parental-behavior-trajectories-differ-across-four-species-deer) PLoS ONE. 2022. p. e0276052. Khadraoui M, Merritt J, Hoekstra H, Bendesky A. [Post-mating parental behavior trajectories differ across four species of deer mice.](/publications/post-mating-parental-behavior-trajectories-differ-across-four-species-deer) PLoS ONE. 2022. p. e0276052. - add\_circle\_outline do\_not\_disturb\_on Abstract - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/khadraoui_0276052.pdf) Among species, parental behaviors vary in their magnitude, onset relative to reproduction, and sexual dimorphism. In deer mice (genus *Peromyscus*), while most species are promiscuous with low paternal care, monogamy and biparental care have evolved at... - [ picture\_as\_pdfPDF](/sites/g/files/omnuum6376/files/hoekstra/files/khadraoui_0276052.pdf) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [4](?page=3 "Go to page 4") - [5](?page=4 "Go to page 5") - [6](?page=5 "Go to page 6") - [7](?page=6 "Go to page 7") - [8](?page=7 "Go to page 8") - [ Next page chevron\_right ](?page=1 "Go to next page")